Should I take him to the ER (experienced mothers only please!)?

I have a 3 month old son. (14 weeks) He started sleeping through the night at 6 weeks. Last night, he fell asleep at 11pm and woke up at 2:15 am screaming like I've never heard him scream before. I changed his diaper, fed him, burped him, and rocked him back to sleep. As soon as I put him back down, he started screaming again. I picked him back up, he fell asleep in my arms, I put him down, he instantly started screaming again. This continued until about 5am when instead of putting him in his binet, I just lay him down on his boppy pillow. I talked to the nurse at his Dr's office earlier this evening and asked if my son was congested or had a fever or high temp, which he didn't. The advice given to me was to get a sling or carrier and just keep him close for now since that's what seems to make him happy, and even to let him sleep in my bed with me. Also to give him baby Tylenol, and to take him to the ER if he was still fussy tonight. Well, I didn't get the Tylenol because I'm not comfortable giving my baby medicine unless he's seen by his Dr. Well, now, he is very stuffy, has clear snot and white boogers draining from his nose, his eyes are red and he's rubbing them a lot. He's no longer fussy, and doesn't have a fever or high temp, but he actually does seem sick now. The after hours call center for his Dr. is not answering. Should I take my son to the ER or wait until morning to get a hold of his Dr.?